Neurochemical Mechanisms of Alcohol Reinforcement
Serotonin
- alcohol decreases serotonin concentrations in some parts of the brain, it increases it in others
- brain of P rats contain lower concentrations of serotonin than wild type rats.
- Serotonin agonists reduce alcohol intake
- Serotonin antagonists also reduce alcohol intake???
- Conflicting evidence reflects current lack of understanding of processes that serotonin controls